(2SR,4aSR,8aSR)-6-Oxoperhydronaphthalene-2-carboxylic acid
نویسندگان
چکیده
In the title racemic compound, C(11)H(16)O(3), the mol-ecule adopts a conformation that places its carboxyl group in an equatorial position. Mol-ecules aggregate by hydrogen-bond pairing of carboxyl groups, yielding centrosymmetric dimers that are arranged into layers in the (020) planes.
منابع مشابه
Synthesis and Photosynthesis-Inhibiting Activity of Some Anilides of Substituted Pyrazine-2-carboxylic Acids
Alkylation of pyrazine-2-carboxylic acid and 6-chloropyrazine-2-carboxylic acid with radicals generated by silver nitrate-catalyzed oxidative decarboxylation of pivalic acid afforded 5-(1,1dimethylethyl)pyrazine-2-carboxylic acid and 6-chloro-5-(l,l-dimethylethyl)pyrazine-2-carboxylic acid. Condensation of chlorides of the latter three halogenated and/or alkylated pyrazine-2carboxylic acids wit...
متن کاملSubstituted pyrazinecarboxamides: synthesis and biological evaluation.
Condensation of the corresponding chlorides of some substituted pyrazine-2-carboxylic acids (pyrazine-2-carboxylic acid, 6-chloropyrazine-2-carboxylic acid, 5-tert-butylpyrazine-2-carboxylic acid or 5-tert-butyl-6-chloropyrazine-2-carboxylic acid) with various ring-substituted aminothiazoles or anilines yielded a series of amides. The syntheses, analytical and spectroscopic data of thirty newly...
متن کاملSynthesis and biological activity of N-substituted-3-chloro-2-azetidinones.
2-Aminobenzothiazole-6-carboxylic acid (1), on condensation with chloroacetyl chloride yielded 2-(2-chloroacetylamino)benzothiazole-6-carboxylic acid (2), which on amination with hydrazine hydrate yielded in turn 2-(2-hydrazinoacetylamino)benzo-thiazole-6-carboxylic acid (3). Compound 3, on condensation with various aromatic aldehydes afforded a series of 2-{2-[N'-(arylidene)hydrazino]acetylami...
متن کامل[3 + 2] Cycloaddition reactions of thioisatin with thiazolidine-2-carboxylic acid: a versatile route to new heterocyclic scaffolds
A facile synthesis of azabicycloadducts is described by 1,3-dipolar cycloaddition reactions of thioisatin with thiazolidine-2-carboxylic acid in the presence of various electron rich and electron deficient dipolarophiles. Theoritical calculations have been performed to study the regioselectivity of products. The geometrical and energetic properties have been analyzed for the different reactants...
متن کاملHeterocycles [h]fused onto 4-oxoquinoline-3-carboxylic acid, part IV. Convenient synthesis of substituted hexahydro [1,4]thiazepino[2,3-h]quinoline-9-carboxylic acid and its tetrahydroquino[7,8-b]benzothiazepine homolog.
Substituted [1,4]thiazepino[2,3-h]quinolinecarboxylic acid 3 is prepared by PPA-catalyzed thermal lactamization of the respective 8-amino-7-[(2-carboxyethyl)thio]-1,4-dihydroquinoline-3-carboxylic acid 9. The latter synthon is obtained by reduction of the 8-nitro-1,4-dihydroquinoline precursor 8 which, in turn, is made accessible via interaction of 3-mercaptopropionic acid with 7-chloro-1-cyclo...
متن کامل